π¬ How to Enhance Reproducibility in Biosimilar Research
Biosimilar research requires complex experimental workflows and strict quality control, making lab automation a crucial technology for overcoming these challenges. Reproducibility and precision are essential for successful biosimilar development, and the adoption of automation solutions is steadily increasing.
*οΈβ£The Role of Lab Automation in Biosimilar Development Biosimilars must demonstrate high similarity to the reference biologic, requiring extensive physicochemical analyses and biological assays. Automated liquid handling systems and high-throughput screening (HTS) platforms help standardize these processes, reduce manual workload, and accelerate research.
Key Experimental Steps Requiring Automation
β Cell Culture & Maintenance β Ensuring a uniform environment for organoid and cell line development β Sample Preparation & Analysis β Precision pipetting automation for ELISA, qPCR, and NGS experiments βBioassay for Activity Comparison β Evaluating biological equivalence between biosimilars and reference drugs
*οΈβ£ Automated Solutions for Reproducibility and Accuracy
A lack of reproducibility in biosimilar research can pose significant risks during regulatory approval. Automation systems provide consistent liquid handling, uniform sample processing, and error-free analysis, improving data reliability and compliance.
*οΈβ£ The Importance of HTS and Automated Pipetting Systems Given the need for rapid data analysis and sample processing, HTS and automated pipetting systems play a critical role in enhancing research efficiency.
Benefits of Automated HTS & Pipetting Systems
β High-Speed Sample Processing β Quickly and accurately analyzing large sample volumes, reducing research timelines β Minimized Variability β Reducing human error and ensuring a standardized lab environment β Cost Reduction β Decreasing reagent waste, reducing consumables usage, and minimizing the need for repetitive experiments
SUITABLE, with its independently controlled 8-span pipetting system and large 24-slot deck, is an ideal solution for performing multiple biosimilar research experiments simultaneously.
Curious about ABLE Labs' SUITABLE? Click the link below to download our brochure and explore its capabilities.